L-5-Methyltetrahydrofolate Calcium

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What is L-5-Methyltetrahydrofolate Calcium

L-5-Methyltetrahydrofolate Calcium, which is an active form of folic acid. Folic acid itself is a water-soluble vitamin that requires a series of metabolic transformations in the human body to play its role. L-5-Methyltetrahydrofolate Calcium does not need to go through this complex metabolic process, and can be directly absorbed and utilized by the human body.

Common folic acid (synthetic folic acid) is mainly a supplement form of folic acid. After the human body ingestion of ordinary folic acid, it needs to be catalyzed by a variety of enzymes in the body, such as methylene tetrahydrofolate reductase (MTHFR), to convert it into 5-methyltetrahydrofolate in order to play its physiological functions. So L-5-Methyltetrahydrofolate Calcium is the most effective way to supplement folic acid.

 

Benefits of L-5-Methyltetrahydrofolate Calcium

  • L-5-Methyltetrahydrofolate Calcium & Depression

Folic acid deficiency increases the risk of depression. L-5-Methyltetrahydrofolate Calcium can be used with depression medications. It is beneficial to the efficacy of the medicine.

  • Methylfolate Supplement for Pregnant Female

L-5-Methyltetrahydrofolate Calcium protects red blood cells. Folic acid deficiency leads to anemia during pregnancy and birth defects. From the fertilized egg to the development of the brain, heart, and other organs until birth, it also plays an important role in the entire life cycle. It is involved in cellular DNA synthesis, repair, and regulation.

  • L-5-Methyltetrahydrofolate Calcium for Men, Brain & Immune System

Doctors recommend that men should also take folic acid during pregnancy preparation to improve sperm motility. At the same time, this ingredient can also improve immunity and support health. This ingredient protects cardiovascular and cerebrovascular diseases, improves cognitive ability, and prevents Alzheimer’s.

 

Why Choose L-5-Methyltetrahydrofolate Calcium Instead of Folic Acid?

  • Security

L-5-Methyltetrahydrofolate Calcium is an endogenous basic substance in the human body, so it will not cause adverse reactions such as allergies. The long-term application practice of more than ten years in Europe and the United States shows that artificial L-5-Methyltetrahydrofolate Calcium can be comparable to endogenous L-5-Methyltetrahydrofolate Calcium as long as it is stable enough and pure enough.

  • Effectiveness

L-5-Methyltetrahydrofolate Calcium is superior to synthetic inactive folic acid in terms of effectiveness, because synthetic inactive folic acid needs to be converted into L-5-Methyltetrahydrofolate Calcium by folic acid metabolism enzymes in the body before it can be used. However, due to the gene mutation of this key metabolic enzyme, its genotype is different, resulting in the ability of some people to convert inactive synthetic folic acid into active folic acid is reduced, resulting in folic acid metabolism disorders, affecting the normal biological effects of folic acid in the body. As L-5-Methyltetrahydrofolate Calcium is not affected by the conversion of folic acid metabolic enzymes, it can be directly absorbed and utilized by all people, and is not restricted by race and region, so for people with folic acid metabolism disorders, the use of active folic acid has a wider effectiveness and is a better choice to supplement folic acid.

  • Absorptivity

The amount of L-5-Methyltetrahydrofolate Calcium that can be obtained through the conversion of inactive folic acid in the body is limited and varies by population (genotype). Direct intake of active folic acid does not exist in the body conversion link, which can ensure that the intake dose is quickly absorbed to obtain the required accurate dose.

Clinical trial

Items

Dosage Intake

Effectiveness

Bipolar I Depression

15mg/day

Major Depressive Disorder (MDD)

15mg/day

Promoting Recovery from Metal Illness

15mg/day

Treatment of Type 2 Diabetes with Peripheral Neuropathy

3mg/day

Prevention of Cardiovascular Health

2mg/day

 

Specifications:

Appearance

White to light yellow crystalline powder, odorless

Content (on dry basis, HPLC)

95.0%~102.0%

Water

6.0%~17.0%

Calcium (on dry basis, HPLC)

7.0%~8.5%

Residual Solvents (Ethanol)

≤0.5%

 

Storage:

Store in cool and dry place, keep away from heat and sunlight.

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